// head_to_head

GPT-5.4 Nano vs Qwen2.5 72B Instruct

Published LiveBench scores across all seven categories, live list pricing, context windows, and the measured cost of a point of capability — for both models, side by side.

OpenRouter + LiveBenchAll comparisonsFull leaderboard

Qwen2.5 72B Instruct is the cheaper of the two; neither can be ranked on quality here.

Qwen2.5 72B Instruct does not have a published LiveBench run, so this comparison covers price, context and declared capabilities only. A missing score means "not evaluated", not "worse" — the right way to separate these two is an eval on your own workload.

openai

GPT-5.4 Nano

Blended / 1M
$0.463
Context
400K
Released
Mar 17, 2026
Overall score
69.6
reasoningtool callingfile inputimage inputprompt caching

qwen

Qwen2.5 72B Instruct

Blended / 1M
$0.370
Context
33K
Released
Sep 19, 2024
Overall score
Not evaluated
tool calling

Specs and pricing

MetricGPT-5.4 NanoQwen2.5 72B Instruct
LiveBench overall

Mean of the seven LiveBench category scores, 0–100. Higher is better.

69.6
Cost per point

Measured benchmark spend divided by overall score — dollars per point of capability.

$0.0500
Blended price / 1M

3:1 input:output mix, the usual shape of production traffic.

$0.463$0.370win
Input price / 1M$0.200win$0.360
Output price / 1M$1.25$0.400win
Cached input / 1M

Price of an input token served from the prompt cache, where the provider publishes one.

$0.020
Context window400Kwin33K
Max output tokens128Kwin16K

Benchmarks by category

An overall score averages away the thing you probably care about. These are the seven LiveBench categories scored separately — GPT-5.4 Nano on top, Qwen2.5 72B Instruct below, both out of 100.

Agentic coding
46.8
Coding
70.8
Reasoning
81.1
Mathematics
91.0
Data analysis
67.6
Language
62.5
Instruction following
67.2

What each one costs to run

Per-token prices are hard to feel. These are monthly list costs for both models across five workload shapes, using each provider's published cached-input rate where there is one.

WorkloadGPT-5.4 NanoQwen2.5 72B Instruct
Support chatbot

1.2K in / 400 out × 200K requests

$135.04/mo$118.40/mo
RAG assistant

8K in / 600 out × 100K requests

$163.00/mo$312.00/mo
Coding agent

40K in / 4K out × 20K requests

$159.20/mo$320.00/mo
Document extraction

20K in / 1.5K out × 50K requests

$284.75/mo$390.00/mo
Bulk classification

500 in / 20 out × 5M requests

$535.00/mo$940.00/mo
Run these two through the cost calculator

Which should you pick?

You need to fit large documents in one call

GPT-5.4 Nano

Wider context window — 400K against 33K.

You are cost-constrained

Qwen2.5 72B Instruct

Cheaper on blended list price at $0.370 per million tokens.

GPT-5.4 Nano vs Qwen2.5 72B Instruct FAQ

Which is better, GPT-5.4 Nano or Qwen2.5 72B Instruct?

Qwen2.5 72B Instruct is the cheaper of the two; neither can be ranked on quality here. Qwen2.5 72B Instruct does not have a published LiveBench run, so this comparison covers price, context and declared capabilities only. A missing score means "not evaluated", not "worse" — the right way to separate these two is an eval on your own workload.

Is GPT-5.4 Nano cheaper than Qwen2.5 72B Instruct?

Qwen2.5 72B Instruct is cheaper. On a 3:1 input:output blend, GPT-5.4 Nano lists at $0.463 per million tokens and Qwen2.5 72B Instruct at $0.370 — Qwen2.5 72B Instruct is 25% cheaper. Input and output are priced separately — GPT-5.4 Nano charges $0.200 in and $1.25 out, Qwen2.5 72B Instruct charges $0.360 and $0.400 — so the model that looks cheaper flips depending on how output-heavy your workload is.

Does GPT-5.4 Nano or Qwen2.5 72B Instruct have a bigger context window?

GPT-5.4 Nano has the larger context window: 400K for GPT-5.4 Nano against 33K for Qwen2.5 72B Instruct. Note that a window you can fill is not a window you should fill — retrieval quality usually degrades well before the limit, and you pay for every token you put in it.

Do GPT-5.4 Nano and Qwen2.5 72B Instruct support prompt caching?

GPT-5.4 Nano publishes a cached-input rate of $0.020 per million tokens against a full input rate of $0.200. The catalogue lists no separate cached rate for Qwen2.5 72B Instruct, which means the provider does not price it separately here — not that caching is unavailable.

Related comparisons

How these numbers are produced

  • Price — provider list price from OpenRouter, refreshed every 15 minutes. “Blended” is a 3:1 input:output mix.
  • ScoresLiveBench release 2026-06-25, using their own category map. Each model shows its strongest published run. A blank means “not evaluated”, never “bad”.
  • Cost per point — the measured dollars LiveBench spent on the run, divided by the score it earned.
  • “Win” — awarded only past a threshold: one full point on a benchmark score, 10% on a price, 25% on a context window. Anything tighter reports as a tie, because effort settings alone move a LiveBench score by more than that.

Published benchmarks rank models on someone else's tasks. Before committing, see LLM & agent evaluation for building an eval on your own.